The document contains selected regional considerations on safe and inclusive transport and mobility in the Asia-Pacific region, highlighting the potential areas for regional cooperation on transport and related activities of the Economic and Social Commission for Asia and the Pacific for reducing poverty, promoting gender equality and supporting social inclusion in the context of the 2030 Agenda for Sustainable Development. The present document also contains updated information on the secretariat’s recent and ongoing activities on the relevant thematic areas of the Regional Action Programme for Sustainable Transport Connectivity in Asia and the Pacific, phase I (2017–2021).