This study highlights the economic consequences of excluding people with disabilities from participating in the employment sector. It uses data from ten low and middle-income developing countries in Asia (China, Thailand and Viet Nam) and in Africa (Ethiopia, Malawi, Namibia, South Africa, Tanzania, Zambia and Zimbabwe) to understand the relationship between economic losses and disability. It found that economic losses related to disability are large and measurable, ranging from between 3 and 7 per cent of a nation's total GDP. The findings of the study can help governments in allocating resources to economic development and livelihoods/employment program relating to the employability people with disabilities.